Sulfur-Based Chiral Iodoarenes: An Underexplored Class of Chiral Hypervalent Iodine Reagents

Abstract Chiral hypervalent iodine reagents are active players in modern stereoselective organic synthesis. Structurally diverse chiral have been synthesised and extensively studied, but containing sulfur stereogenic centre scarce their synthesis is challenging. A small library of iodoarenes sulfinamide sulfoximine moieties has using commercially available reagents. The oxidation the iodoarene precursors to iodine(III) was cumbersome due facile overoxidation sulfoxide moiety hence loss chirality under various conditions. Oxidation sulfonimidoyl derivatives corresponding successful led novel sulfur-based